Spectrum: Local Antimicrobial Stewardship, for UCLA Health

Ceftazidime

C. diff Risk

Medium

Oral Bioavailability

NA

Approximate Cost

$$

Spectrum Of Activity

General Spectrum of Activity

Spectrum Of Activity

General Spectrum of Activity

Antibiogram Data

General Information

Common Usage

Common Usage

Broad gram negative coverage including Pseudomonas, generally used for nosocomial infections including post-neurosurgical meningitis, or other infections based on susceptibilities.

Notable lack of gram positive activity versus other cephalosporins

Adverse Effects

Adverse Effects

Allergy (immediate and delayed). Note potential cross-reactivity with aztreonam based on side chain

Pharmacology

Pharmacology

Antimicrobial class: 3rd generation Cephalosporin

Pregnancy category: B

Average serum half life: 2 hours

Biliary penetration: Moderate

CSF penetration: Therapeutic

Lung penetration: Therapeutic

Urine penetration: Therapeutic