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Pathogens
Antimicrobials
Medium
NA
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Broad spectrum agent with anti-pseudomonal activity used for severe infections including pneumonia, intra abdominal/hepatobiliary, UTI, polymicrobial skin and soft tissue infection, and febrile neutropenia
Laboratory
Allergy/rash (immediate or delayed)
Cytopenias- esp. thrombocytopenia
Eosinophilia
Interstitial nephritis
Abnormal liver enzymes
Incr. levels of methotrexate
Use with caution for CNS infections
Alternate dosing may be necessary for special populations, e.g. cystic fibrosis and morbid obesity
Antimicrobial class: Ureidopenicillin with a beta-lactamase inhibitor
Pregnancy category: B
Average serum half life: 1 hour
Biliary penetration: Therapeutic
CSF penetration: Poor
Lung penetration: Therapeutic
Urine penetration: Therapeutic