Medium
NA
$$
5 mg/kg IV x 1, then 5 mg/kg/day IV divided into 2-3 doses, adjusted for renal function and dialysis
75 mg q12h inhaled
Infections due to non-MDR pathogens for which alternate therapy, particularly beta-lactam antibiotics, are available
Prophylaxis
Severe infectious caused by multidrug-resistant Gram-negative organisms when other antimicrobial options are limited
Laboratory
Clinical
Nephrotoxicity in up to 20% of patients
Phlebitis at infusion sites
Neurotoxicity
Inhaled form: Possible bronchospasm, ARDS
