Spectrum: Local Antimicrobial Stewardship, for Markham Stouffville Hospital

General Information

Policy

Early conversion from intravenous (IV) to oral (PO) antimicrobials therapy is effective for a variety of infections.

Many oral antimicrobials have excellent bioavailability and conversion from IV to PO antimicrobials therapy in selected patients is an effective way of achieving the following:

  • Shortened length of hospital stay

  • Reduced risk of line-related infections and adverse events

  • No IV-related mobility restrictions for patients

  • Cost savings through medication preparation/administration, IV supplies, and drug costs

The switch or step-down to oral therapy must be individualized based upon the patient’s clinical status and infection.