At-Risk Infants

Consider infants at-risk that are born by any delivery method to a mother with either HSV genital lesions at delivery or during the postpartum hospitalization, or a positive maternal HSV culture at delivery, regardless of the nature of the maternal infection status (e.g., primary or recurrent)

See below for factors that might increase disease transmission to infants

• Primary genital infection

• Cervical or vaginal rather than vulvar lesions

• Status (primary or recurrent) is unknown

• Prolonged rupture of membranes more than 4 hours

• Prematurity (37 or fewer weeks’ gestation)

• Fetal scalp electrode monitor

• Skin trauma or laceration at delivery