Definitions

Generally presents at or within 24 hours of birth but can occur within the first seven days of life.

Usually, it will present as sepsis without a focus, pneumonia, or meningitis.

Usually occurs at four to five weeks of age (range 7 to 89 days).

Most often, it presents as bacteremia with or without a focus.

If with a focus, it usually manifests as: meningitis, pneumonia, septic arthritis, osteomyelitis, cellulitis, and adenitis.

Also called very-late-onset GBS or GBS beyond early infancy.

Occurs in infants older than three months of age (>89 days).

Late, late-onset GBS infections are most common in infants who are born before 28 weeks' gestation or in children with a history of immunodeficiency.

It typically manifests as bacteremia without a focus, but focal sites of infection may be noted, including the CNS, soft tissues, bones and joints, and intravascular catheters.