Spectrum: Local Antimicrobial Stewardship, for Markham Stouffville Hospital

CDI, IAI or Perianal Abscess

For Clostridium difficile Infection

ADD

Vancomycin PO*

See MSH *Clostridium Difficile Infection (CDI) guideline.

If fulminant disease add Metronidazole 500 mg IV q8h

Note - Probiotics are contraindicated in immunocompromised patients.

For Intra-Abdominal Infections or Perianal Abscess

ADD

Metronidazole 500 mg PO/IV q12h*

*If not on an agent that covers anaerobes (not needed if on Piperacillin-Tazobactam or Meropenem)