Spectrum: Local Antimicrobial Stewardship, for Markham Stouffville Hospital

Antimicrobial Duration

Community Acquired Pneumonia

Short: 3 or 5 days

Long: 7-14 days

Equal efficacy in 9 RCTs

Ventilator Associated Pneumonia

Short: 8 days

Long: 15 days

Equal efficacy in 2 RCTs

Pyelonephritis

Short: 7 or 5 days

Long: 14 or 10 days

Equal efficacy in 7 RCTs

Intra-abdominal Infections

Short: 4 days

Long: 10 days

Equal efficacy in 2 RCTs

GNB Bacteremia

Short: 7 days

Long: 14 days

Equal efficacy in 1 RCT*

Acute Exacerbation of Chronic Bronchitis

Short: less than or equal to 5 days

Long: greater than or equal to 7 days

Equal efficacy in more than 20 RCTs

Cellulitis

Short: 5-6 days

Long: 10 days

Equal efficacy in 3 RCTs

Chronic Osteomyelitis

Short: 42 days

Long: 84 days

Equal efficacy in 2 RCTs

Foot Notes and References

*GNB bacteremia also in UTI/cIAI RCTs

Full chart and references available here