Spectrum: Local Antimicrobial Stewardship, for Markham Stouffville Hospital

Hematogenous Osteomyelitis - Adolescents and Adults

Common Pathogens

Staphyloccocus aureus

MRSA Risk Factors:

  • Evidence of MRSA infection elsewhere

  • Nasal colonization with MRSA

  • Injection drug use

Enterobacteriaceae

Empiric IV Antimicrobial Regimen

Cefazolin 2g IV Q8H

β-Lactam Anaphylaxis

Ertapenem 1g 1V q24H

MRSA Risk Factors Present

ADD

Vancomycin 15-20mg/kg

IV Q8-12H