Spectrum: Local Antimicrobial Stewardship, for Markham Stouffville Hospital

β-Lactam Allergy (Adults)

Empiric Regimen of Choice

Vancomycin 15-20mg/kg IV Q12H

PLUS

Gentamicin 5-7mg/kg IV Q24H

PLUS

Metronidazole 500mg IV Q12h

ALTERNATIVELY, CONSIDER

Meropenem 500mg IV Q6H

PLUS

Vancomycin 15-20mg/kg IV Q12H

Duration of Therapy

7-10 days, but in general treatment should be extended if the infection has not improved within this time period.