Reservoir is human skin and oropharynx/mucous membranes.
Person-to-person transmission.
Occasionally foodborne.
Exhaustive and fascinating list.
Most common manifestations are:
Tonsillopharyngitis ("Strep throat")
Skin infections (impetigo, erysipelas, cellulitis)
Other invasive infections:
Bacteremia
Endocarditis
Necrotizing fasciitis
Meningitis
Toxic shock syndrome
Pneumonia
Other sterile space infections.
Post-infectious immunologically mediated phenomena such as glomerulonephritis and rheumatic fever.
Scarlet fever.
Droplet precaution not required in endometritis and pharyngitis.
Contact and droplet precautions for invasive disease for the first 24hrs of antimicrobial therapy or after last debridement, otherwise no precautions.
Post-exposure prophylaxis may be indicated.
Disease of Public Health Significance