Spectrum: Local Antimicrobial Stewardship, for Markham Stouffville Hospital

Fidaxomicin

Restricted
Restricted

C. diff Risk

None

Oral Bioavailability

None

Approximate Cost

Spectrum Of Activity

General Spectrum of Activity

Spectrum Of Activity

Dosing

Renal

No adjustment required

Adult

C. difficile
200 mg PO BID x 10 days

General Information

Common Usage

Common Usage

C. difficile colitis

Adverse Effects

Adverse Effects

  •  GI disturbance

  •  Cytopenias

  •  Hypersensitivity: facial, tongue or throat swelling

Additional Information

Additional Information

Consult Infectious Disease (this antimicrobial is restricted to use by ID physicians).

Pharmacology

Pharmacology

Antimicrobial class: Specialized anti-C. difficile macrocyclic agent

Pregnancy category: B

Biliary penetration: None

CSF penetration: None

Lung penetration: None

Urine penetration: None