Spectrum: Local Antimicrobial Stewardship, for Bakersfield Memorial Hospital

Cefuroxime

C. diff Risk

Medium

Oral Bioavailability

Moderate

Approximate Cost

Spectrum Of Activity

General Spectrum of Activity

Spectrum Of Activity

Dosing

Renal

Adult

500 mg PO every 12 hr

General Information

Common Usage

Common Usage

  •  Sinusitis

  •  Pharyngitis/tonsillitis

  •  Epiglottitis

  • Lyme disease

  • Impetigo

Adverse Effects

Adverse Effects

  •  Allergy (immediate & delayed)

  •  Positive Coombs

  •  Cytopenias

  •  GI upset

  •  Diarrhea

  •  Abnormal liver enzymes

Major Interactions

Major Interactions

No significant interactions.

Pharmacology

Pharmacology

Antimicrobial class: 2nd Generation Cephalosporin

Pregnancy category: B

Average serum half life: 2 hours

Biliary penetration: Therapeutic

CSF penetration: Poor

Lung penetration: Therapeutic

Urine penetration: Therapeutic