Gram positive

•  MSSA

•  Susceptible MRSA

•  Group A,B,C,G Streptococci (but increasing resistance)

•  viridans Streptococci

Gram negatives

•  Essentially no aerobic gram negative coverage

Anaerobes

•  Increasing resistance in Bacteroides fragilis

•  Covers many oral anaerobes

Other

•  Pneumocyctis jiroveci

•  Malaria

•  Toxoplasma

Does not cover

•  Almost all aerobic gram negatives

•  Enterococci