Spectrum: Local Antimicrobial Stewardship, for NYC Department of Health

Cephalexin

C. diff Risk

Medium

Oral Bioavailability

Moderate

Approximate Cost

Spectrum Of Activity

General Spectrum of Activity

Spectrum Of Activity

Dosing

Adult

500-1000mg PO QID

Renal

General Information

Common Usage

Common Usage

  •  Uncomplicated skin and soft tissue infection

  •  MSSA infections

Adverse Effects

Adverse Effects

  •  Allergy and rash as for all beta-lactams

  •  Positive Coombs

  •  Cytopenias

  •  Eosinophilia

  •  Hepatic & renal laboratory abnormalities

Major Interactions

Major Interactions

Increases metformin levels

Pharmacology

Pharmacology

Antimicrobial class: First Generation Cephalosporin

Pregnancy category: B

Biliary penetration: Moderate

CSF penetration: Poor

Lung penetration: Moderate

Urine penetration: Therapeutic