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Minimize duration of mechanical ventilation through daily sedation breaks and spontaneous breathing trials in eligible patients, and the use of noninvasive ventilation in some to prevent intubation
Hand hygiene
Maintain the head of bed at 30-45 degrees whenever possible
Use endotracheal tubes with subglotic suction (Evac) with cuff inflated to at least 20cm H20.
Discontinue H2 blockers and PPIs in patients that are no longer high risk (e.g. tolerating enteral nutrition)
Regular oral care
Orotracheal intubation preferred to nasotracheal
Use orogastric tubes instead of nasogastric tubes and initiate enteral nutrition early
Early mobilization