Clinicians should start antiviral treatment as soon as possible for adults and children with documented or suspected influenza, irrespective of influenza vaccination history, who meet the following criteria:
1. Persons of any age who are hospitalized with influenza, regardless of illness duration prior to hospitalization.
2. Outpatients of any age with severe or progressive illness, regardless of illness duration.
3. Outpatients who are at high risk of complications from influenza, including those with chronic medical conditions and immunocompromised patients.
4. Children younger than 2 years and adults ≥65 years.
5. Pregnant women and those within 2 weeks postpartum.