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Consult Infectious Diseases
SIX weeks for MRSA IE
The course starts from the first negative blood culture, and may require alteration if complications occur or the patient requires surgery/valve replacement
If bacteremia persists on Vancomycin, the MIC should be reported - if ≥2µg/mL, a switch to an alternative MRSA drug may be considered
Vancomycin IV loading dose followed by maintenance for target trough of 15-20 ug/mL see dosing nomogram
If patient cannot be dosed using nomogram contact Pharmacy.
OR
Daptomycin 8/mg/kg
IV daily