Spectrum: Local Antimicrobial Stewardship, for Eastern Health

Cephalexin

C. diff Risk

Medium

Oral Bioavailability

Good (70 to 90%)

Approximate Cost

$0.44/day

Spectrum Of Activity

General Spectrum of Activity

Spectrum Of Activity

General Spectrum of Activity

Antibiogram Data

Dosing

Renal

Adult

500-1000mg PO QID

General Information

Common Usage

Common Usage

  •  Uncomplicated skin and soft tissue infection

  •  MSSA infections

Adverse Effects

Adverse Effects

  •  Allergy/rash (immediate or delayed)

  •  Positive Coombs

  •  Cytopenias

  •  Eosinophilia

  •  Hepatic & renal laboratory abnormalities

Coverage

NLPDP Status

OPEN BENEFIT
No prescribing restrictions

Additional Information

Additional Information

EH Prescribing Restrictions
None

Tablets can be crushed and given via NG route; Liquid formulation also available

Pharmacology

Pharmacology

Antimicrobial class: First Generation Cephalosporin.

Pregnancy category: B

Biliary penetration: Moderate

CSF penetration: Poor

Lung penetration: Moderate

Urine penetration: Therapeutic