Spectrum: Local Antimicrobial Stewardship, for Providence Health Care

Vancomycin PO

C. diff Risk

None

Oral Bioavailability

None

Approximate Cost

Spectrum Of Activity

General Spectrum of Activity

Spectrum Of Activity

Dosing

Adult

125mg po QID for 10-14 days

Intra-colonic dose 500mg in 100mL of NS by rectal enema q6h

General Information

Common Usage

Common Usage

Only indication is in the therapy of C. difficile infection, particularly recurrent or severe disease

Additional Information

Additional Information

No oral absorption. May increase vancomycin resistant enterococci colonization in the gut

Pharmacology

Pharmacology

Antimicrobial class: glycopeptide

Pregnancy category: B

Average serum half life: 0.0

Biliary penetration: None

CSF penetration: None

Lung penetration: None

Urine penetration: None