Spectrum: Local Antimicrobial Stewardship, for Providence Health Care

Oseltamivir

C. diff Risk

None

Oral Bioavailability

Excellent

Approximate Cost

Spectrum Of Activity

General Spectrum of Activity

Spectrum Of Activity

Dosing

Renal

Adult

Treatment: 75mg PO BID x 5 days

Prophylaxis: 75mg PO daily until outbreak is over

General Information

Common Usage

Common Usage

Treatment and prophylaxis of influenza A and B

Adverse Effects

Adverse Effects

  • GI upset common

  • Rare - Stevens Johnson

  • Neuropsychiatric side effects reported

Major Interactions

Major Interactions

No significant

Additional Information

Additional Information

Will only treat Influenza A and B. Does NOT treat RSV, parainfluenza, human metapneumovirus, adenovirus, or other common viral pathogens
Higher doses have not been shown to be superior, but may be considered in critically ill or obese patients i.e. 150mg PO BID

Pharmacology

Pharmacology

Antimicrobial class: Antiviral - neuraminidase inhibitor

Pregnancy category: C

Average serum half life: 2.0

Lung penetration: Therapeutic