Spectrum: Local Antimicrobial Stewardship, for Providence Health Care

Micafungin

C. diff Risk

Low

Oral Bioavailability

NA

Approximate Cost

Spectrum Of Activity

General Spectrum of Activity

Spectrum Of Activity

Dosing

Adult

100mg IV daily

General Information

Common Usage

Common Usage

Therapy of suspected and confirmed invasive fungal infections

Adverse Effects

Adverse Effects

  •  Increased liver enzymes

  •  GI upset

Major Interactions

Major Interactions

Increases levels of sirolimus and nifedipine (mild)

Additional Information

Additional Information

Requires ID or Antimicrobial Stewardship approval for onging use without an accepted indication

Pharmacology

Pharmacology

Antimicrobial class: Echinocandin

Pregnancy category: C

Average serum half life: 15.0

Biliary penetration: Therapeutic

CSF penetration: Poor

Lung penetration: Therapeutic

Urine penetration: Poor