Spectrum: Local Antimicrobial Stewardship, for Providence Health Care

Fidaxomicin

Restricted
Restricted

C. diff Risk

None

Oral Bioavailability

None

Approximate Cost

Spectrum Of Activity

General Spectrum of Activity

Spectrum Of Activity

Dosing

Renal

Adult

200mg po BID x 10days for C. difficile

General Information

Common Usage

Common Usage

C. difficile colitis

Drug Monitoring

Drug Monitoring

None

Adverse Effects

Adverse Effects

Hypersensitivity: facial, tongue, or throat swelling

GI disturbance, cytopenias

Additional Information

Additional Information

  • Consult Infectious Disease

  • Non-formulary

  • Minimal systemic absorption

Pharmacology

Pharmacology

Antimicrobial class: Specialized anti-C. diffile macrocyclic agent

Pregnancy category: B

Average serum half life: 0.0

Biliary penetration: None

CSF penetration: None

Lung penetration: None

Urine penetration: None