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Pathogens
Antimicrobials
High
NA
1-2g IV q8h
Broad gram negative coverage including Pseudomonas, generally used for nosocomial infections including post-neurosurgical meningitis, or other infections based on susceptibilities.
Notable lack of gram positive activity versus other cephalosporins
Allergy/rash (immediate or delayed).
Can cause positive Coombs, cytopenias, eosinophilia, and hepatic and renal laboratory abnormalities
Antimicrobial class: 3rd generation Cephalosporin
Pregnancy category: B
Average serum half life: 2.0
Biliary penetration: Moderate
CSF penetration: Therapeutic
Lung penetration: Therapeutic
Urine penetration: Therapeutic