Spectrum: Local Antimicrobial Stewardship, for Chapman University School of Pharmacy

Cefoxitin

Oral Bioavailability

NA

Approximate Cost

Spectrum Of Activity

General Spectrum of Activity

Spectrum Of Activity

Dosing

Adult

2g IV q6h

Renal

Renal adjustments required when CrCL < 50 mL/min

General Information

Acceptable Uses

Brand Name

Mefoxin

Adverse Effects

Adverse Effects

  • Rash

  • Thrombophlebitis

Additional Information

Additional Information
  • Primarily used for surgical prophylaxis (intra-abdominal surgery)

Pharmacology

Pharmacology

Pharmacology: Inhibits cell wall synthesis

Antimicrobial class: Beta-lactam

  • 2nd generation cephalosporin

Pregnancy category: B

Average serum half life: 1 hour

Route of Elimination: Renal