Spectrum: Local Antimicrobial Stewardship, for Chapman University School of Pharmacy

Cefuroxime

Oral Bioavailability

Moderate

Approximate Cost

Spectrum Of Activity

General Spectrum of Activity

Spectrum Of Activity

Dosing

Adult

Renal

Renal adjustments required when CrCL < 20 mL/min

General Information

Acceptable Uses

Brand Name

  • Zinacef (IV)

  • Ceftin (PO)

Adverse Effects

Adverse Effects

Rare

  • Cytopenias

  • AIN

Pharmacology

Pharmacology

Pharmacology: Inhibits cell wall synthesis

Antimicrobial class: Beta-lactam

  • 2nd generation cephalosporin

Pregnancy category: B

Average serum half life: 1 - 2 hours

Route of Elimination: Renal