Penicillin VK

Oral Bioavailability

Moderate

Approximate Cost

Dosing

250-500mg PO q6-8h

Renal adjustments required when CrCl < 10 mL/min

General Information

Adverse Effects

  • GI upset

Rare

  • AIN

  • Cytopenias

Oral Liquids

  • 125mg/5mL suspension

  • 250mg/5mL suspension

Tablet/Capsule Strengths

  • 250mg tablet

  • 500mg tablet

Additional Information

Drug of choice for Strep throat

Pharmacology

Pharmacology: Inhibits cell wall synthesis

Antimicrobial class: Beta-lactam

  • Penicillin

Pregnancy category: B

Average serum half life: 1 hour

Route of Elimination: Renal