Spectrum: Local Antimicrobial Stewardship, for Chapman University School of Pharmacy

Metronidazole

Oral Bioavailability

Excellent

Approximate Cost

Spectrum Of Activity

General Spectrum of Activity

Spectrum Of Activity

Dosing

Adult

500mg IV/PO q8h

General Information

Acceptable Uses

Brand Name

Flagyl

Adverse Effects

Adverse Effects

  • Metallic taste

  • Disulfiram reaction

  • GI upset

Rare

  • Peripheral neuropathies (long-term use)

Tablet/Capsule Strengths

Tablet/Capsule Strengths

  • 250mg tablet

  • 500mg tablet

Pharmacology

Pharmacology

Pharmacology: Inhibits DNA synthesis

Antimicrobial class: Nitroimidazole

Pregnancy category: B

Average serum half life: 8 hours