Spectrum: Local Antimicrobial Stewardship, for Chapman University School of Pharmacy

Rifampin

Oral Bioavailability

Excellent

Approximate Cost

Spectrum Of Activity

General Spectrum of Activity

Spectrum Of Activity

Dosing

Adult

General Information

Acceptable Uses

Brand Name

Rifadin

Adverse Effects

Adverse Effects

  • Increased LFTs

  • Hepatotoxicity

  • Discoloration of bodily fluids (red/orange)

  • Nausea

  • Vomiting

Major Interactions

Major Interactions

Major CYP450 inducer

Tablet/Capsule Strengths

Tablet/Capsule Strengths

  • 150mg capsules

  • 300mg capsules

Pharmacology

Pharmacology

Pharmacology: Inhibits protein synthesis

Antimicrobial class: Rifamycin

Pregnancy category: C

Average serum half life: 3 - 5 hours

Metabolism: Hepatic