Spectrum: Local Antimicrobial Stewardship, for Chapman University School of Pharmacy

Ceftazidime-Avibactam

Oral Bioavailability

NA

Approximate Cost

$$$$

Spectrum Of Activity

General Spectrum of Activity

Spectrum Of Activity

Dosing

Adult

2.5 g IV q8h

Renal

Renal adjustments required when CrCl <50 mL/min

General Information

Acceptable Uses

Brand Name

Avycaz

Adverse Effects

Adverse Effects

  • Diarrhea

  • Vomiting

  • Hypersensitivity reaction

Pharmacology

Pharmacology

Pharmacology: Cell wall synthesis inhibitor

Antimicrobial class: Beta-lactam

  • 3rd generation cephalosporin + beta-lactamase inhibitor

Pregnancy category: B

Average serum half life: 3 hours

Route of Elimination: Renal