Spectrum: Local Antimicrobial Stewardship, for Chapman University School of Pharmacy

Cephalexin

Oral Bioavailability

Moderate

Approximate Cost

Spectrum Of Activity

General Spectrum of Activity

Spectrum Of Activity

Dosing

Adult

500mg PO QID
or
1000mg PO BID

Renal

Renal adjustments required when CrCl < 30 mL/min

General Information

Acceptable Uses

Brand Name

Keflex

Adverse Effects

Adverse Effects

  • GI upset

  • Diarrhea

Oral Liquids

Oral Liquids

  • 125mg/5mL suspension

  • 250mg/5mL suspension

Tablet/Capsule Strengths

Tablet/Capsule Strengths

  • 250mg capsule

  • 500mg capsule

  • 750mg capsule

Pharmacology

Pharmacology

Pharmacology: Inhibits cell wall synthesis

Antimicrobial class: Beta-lactam

  • First generation cephalosporin

Pregnancy category: B

Average serum half life: 1 hour

Route of Elimination: Renal