Spectrum: Local Antimicrobial Stewardship, for Prisma Health-Midlands

Human/Animal Bites

Treatment

Irrigation, debridement, and updating tetanus toxoids, if indicated

Empiric Antimicrobial Therapy

Ampicillin/sulbactam 3G IV Q6h

OR

Cefoxitin 2G IV Q6-8h

De-escalation

De-escalation to oral antibiotics based on tissue cultures

Amoxicillin-clavulanate 875mg PO Q12h

If cultures show no growth