General Spectrum of Activity

Gram positive

  • MSSA

  • Susceptible MRSA

  • Group A,B,C,G Streptococci (but increasing resistance)

  • Viridans Streptococci

Gram negatives

  • Essentially no aerobic gram negative coverage

Anaerobes

  • Increasing resistance in Bacteroides fragilis

  • Covers many oral anaerobes

Other

  • Pneumocyctis jiroveci

  • Malaria

  • Toxoplasma

Does not cover

  • Almost all aerobic gram negatives

  • Enterococci