Spectrum: Local Antimicrobial Stewardship, for Prisma Health-Midlands

Cephalexin

C. diff Risk

Medium

Oral Bioavailability

Moderate

Approximate Cost

ยข

Spectrum Of Activity

General Spectrum of Activity

Spectrum Of Activity

Dosing

Adult

500-1000mg PO QID

Renal

General Information

Common Usage

Common Usage

  • Uncomplicated skin and soft tissue infection

  • MSSA infections

Adverse Effects

Adverse Effects

  • Allergy/rash (immediate or delayed)

  • Positive Coombs

  • Cytopenias

  • Eosinophilia

  • Hepatic & renal laboratory abnormalities

Major Interactions

Major Interactions

Increases metformin levels

Pharmacology

Pharmacology

Antimicrobial class: First Generation Cephalosporin.

Pregnancy category: B

Biliary penetration: Moderate

CSF penetration: Poor

Lung penetration: Moderate

Urine penetration: Therapeutic