Microbiology

These are common colonizers in diabetic foot ulcers, especially when identified on sub-optimally collected specimens.

Expanding antimicrobial coverage to include Pseudomonas or Enterococcus when found on culture is only necessary if patient is failing initial empiric regimen.

Deep tissue involvement increases risk of gram negative bacilli

Necrotic, gangrenous, or foul-smelling wounds suggests involvement of mixed anaerobes