S. aureus | Spectrum

Remove line. Catheter retention strongly discouraged.

Treatment

Initiate therapy with and continue vancomycin (high target trough level) until susceptibilities available.

If MSSA, Change Therapy To

Cloxacillin 2g IV q4h

OR

Cefazolin 2g IV q8h

Repeat blood cultures q24-48h until negative.

Duration of therapy (minimum 10 days parenteral) depends on presence of complications (e.g. endocarditis) and persistence of bacteremia.

ID consult is strongly recommended.