Necrotizing Pancreatitis

No antibiotic therapy recommended

Guidelines are against prophylactic antibiotics without confirmed infected necrosis

Controversy exists as some meta-analyses show benefit for early antibiotics in reducing infection; however trials often lack a confirmed microbiological diagnosis and are highly heterogeneous

Consider extrapancreatic infection (e.g. HAP, bloodstream)

if patient unwell and an ID consult

Enteral nutrition vs. TPN has been shown to decrease infectious complications