Spectrum: Local Antimicrobial Stewardship, for Island Health

Cephalexin

C. diff Risk

Medium

Oral Bioavailability

Moderate

Approximate Cost

$1/day

Spectrum Of Activity

General Spectrum of Activity

Spectrum Of Activity

General Spectrum of Activity

Antibiogram Data

Dosing

Adult

500-1000mg PO QID

Renal

General Information

Common Usage

Common Usage

  •  Uncomplicated skin and soft tissue infection

  •  MSSA infections

Adverse Effects

Adverse Effects

  •  Allergy/rash (immediate or delayed)

  •  Diarrhea

  •  Positive Coombs

  •  Cytopenias

  •  Eosinophilia

  •  Hepatic & renal laboratory abnormalities

Major Interactions

Major Interactions

Increases metformin levels.

Pharmacology

Pharmacology

Antimicrobial class: First generation cephalosporin - oral

Pregnancy category: B

Biliary penetration: Moderate

CSF penetration: Poor

Lung penetration: Moderate

Urine penetration: Therapeutic