Gram positive

•  Group A,B,C,G Streptococci

•  MSSA

•  viridans Streptococci

Gram negative

•  Susceptible E. coli

•  Susceptible Klebsiella

•  Susceptible Proteus

Notable Holes in Spectrum

•  H. influenzae

•  Enterococci

•  MRSA

•  Atypicals

•  Many gram negatives

•  Anaerobes