Spectrum: Local Antimicrobial Stewardship, for Yangon Children's Hospital

Significant + Asymptomatic Hypertension

Treatment

Treat fluid overload, which is the usual cause

Do not use ACE inhibitors, as these can worsen renal function

Beta blockers can exacerbate hyperkalaemia

If Euvolaemic

Nifedipine 200-300 µg/kg 3 times daily, starting dose

OR

Amlodipine 100-200 µg/kg once daily, starting dose

If Hypervolemic

Frusemide