Spectrum: Local Antimicrobial Stewardship, for Yangon Children's Hospital

Children ≥8 or <8 with Severe TB or HIV

Intensive Phase

Isoniazid (H) 10 (10-15) mg/kg daily (max: 300mg/day), for 2 months

AND

Rifampicin (R) 15 (10-20) mg/kg daily (max: 600mg/day), for 2 months

AND

Pyrazinamide (Z) 35 (30-40) mg/kg daily, for 2 months

AND

Ethambutol (E) 20 (15-25) mg/kg daily, for 2 months

Continuation Phase

Isoniazid (H) 10 (10-15) mg/kg daily (max: 300mg/day), for 4 months

AND

Rifampicin (R) 15 (10-20) mg/kg daily (max: 600mg/day), for 4 months