NA
Moderate
Rifampicin reduces lumefantrine exposure.
Lumefantrine interacts with various antiretroviral drugs
Tablets contain 20 mg artemether and 120 mg lumefantrine or 40 mg artemether and 240 mg lumefantrine
Give the second dose 8 hours after the first. Lumefantrine absorption is improved by coadministration with a small amount of fat e.g. milk.
Antimicrobial class: Fluorene derivative belonging to the aryl-amino alcohol class
Average serum half life: 33 to 275 h
