Gram positive: Methicillin Susceptible Staphylococcus aureus (MSSA) and susceptible Methicillin Resistant Staphylococcus aureus (MRSA), most streptococci (but increasing resistance with Group B streptococcus), viridans streptococci
Anaerobes: Increasing resistance in Bacteroides fragilis; covers many oral anaerobes
Other: Pneumocyctis jiroveci, malaria, toxoplasmosis
Does not cover: Almost all aerobic gram negatives, enterococci