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Pathogens
Antimicrobials
Low
NA
$100/day
No dosage adjustment required in patients with renal impairment
Therapy of suspected and confirmed invasive fungal infections
Periodic liver function tests, renal function tests, CBC with differential
Increased liver enzymes, elevated bilirubin
GI upset, diarrhea
Pruritis, fever (most common in pediatrics)
Cyclosporin and tacrolimus (drug level monitoring recommended)
Pentrates poorly into CSF and urine.
Antimicrobial class: Echinocandin