Spectrum: Local Antimicrobial Stewardship, for Saskatchewan Health Authority - Saskatoon Area

Vancomycin Resistant IE - Treatment

Strongly consider Infectious Diseases consultation. Infective endocarditis secondary to VRE is an uncommon diagnosis with uncertain optimal therapy.

Suggested Regimen

Linezolid 600 mg PO/IV q12h

OR

Daptomycin 10-12mg/kg IV daily