Home
Guidelines
Pathogens
Antimicrobials
Strongly consider consultation with Infectious Diseases.
Six weeks of therapy.
The course starts from the first negative blood culture, and may require alteration if complications occur or the patient requires surgery/valve replacement
Vancomycin 25 mg/kg IV load followed by 15mg/kg IV maintenance for a target trough of 15-20mg/L
View vancomycin nomogram
Gentamicin and/or rifampin SHOULD NOT be used for treatment of Staphylococcus aureus native valve infective endocarditis. Addition of these agents has not been shown to provide clinical benefit and increases risk of toxicity and drug interactions.
