Spectrum: Local Antimicrobial Stewardship, for Saskatchewan Health Authority - Saskatoon Area

Cephalexin

C. diff Risk

Medium

Oral Bioavailability

Moderate

Spectrum Of Activity

General Spectrum of Activity

Spectrum Of Activity

General Spectrum of Activity

Antibiogram Data

Dosing

Renal

Adult

Usual dose
500mg PO QID

General Information

Common Usage

Common Usage

Cephalexin is commonly used in the treatment of skin and soft tissue infections.

Adverse Effects

Adverse Effects

  • Allergy/rash

  • Positive Coombs test

  • Cytopenias

  • Hepatic & renal laboratory abnormalities

  • Clostridium difficile associated diarrhea

Major Interactions

Major Interactions

Increases metformin levels

Pharmacology

Pharmacology

Antimicrobial class: First Generation Cephalosporin.

Pregnancy category: B

Biliary penetration: Moderate

CSF penetration: Poor

Lung penetration: Moderate

Urine penetration: Therapeutic