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Pathogens
Antimicrobials
High
NA
Usual dosing 2g IV q8-12h
Febrile neutropenia 2g IV q8h
This antimicrobial is restricted to Infectious Diseases, Stem Cell Transplant, Hematology-Oncology and Respirology
Cefepime is a broad-spectrum antimicrobial with Gram positive and Gram negative coverage including activity against Pseudomonas spp.
Cefepime is often used in the treatment of febrile neutropenia and nosocomial infections involving multi-drug resistant organisms.
Use must be approved by Infectious Diseases
Allergy/rash
Positive Coombs test
Cytopenias
Clostridium difficile associated diarrhea
Antimicrobial class: 4th Generation Cephalosporin
Pregnancy category: B
Average serum half life: 2 hours
Biliary penetration: Moderate
CSF penetration: Therapeutic
Lung penetration: Therapeutic
Urine penetration: Therapeutic