High Target - SCr 161-180umol/L

Age 20-29

q18-24h dosing interval

If more aggressive therapy desired, select the more frequent dosing interval

Patients with unstable and/or reduced renal function, nomogram may not be as predictive

Age 30-39

q24h dosing interval

Patients with unstable and/or reduced renal function, nomogram may not be as predictive

Age 40-49

q24h dosing interval

Patients with unstable and/or reduced renal function, nomogram may not be as predictive

Age 50-59

q24h dosing interval

Patients with unstable and/or reduced renal function, nomogram may not be as predictive