High Target - SCr 121-140umol/L

Age 20-29

q12h dosing interval

Age 30-39

q18h dosing interval

Patients with unstable and/or reduced renal function, nomogram may not be as predictive

Age 40-49

q18h dosing interval

Patients with unstable and/or reduced renal function, nomogram may not be as predictive

Age 50-59

q18h dosing interval

Patients with unstable and/or reduced renal function, nomogram may not be as predictive

Age 60-69

q18h dosing interval

Patients with unstable and/or reduced renal function, nomogram may not be as predictive

Age 70-79

q18-24h dosing interval

If more aggressive therapy is desired, select a more frequent dosing interval

Patients with unstable and/or reduced renal function, nomogram may not be as predictive